Ancestry of European Americans

European Americans are …a structured population due to historical immigration of diverse source populations. Discerning the ancestry of European Americans genotyped in association studies is important in order to … identify genetic variants whose contribution to disease risk differs across European ancestries.

…analyzing 4,198 samples from four genome-wide association studies ..shows components roughly corresponding to Northwest European, Southeast European, and Ashkenazi European ancestry are the main sources of European American population structure.

via PLOS Genetics: Discerning the Ancestry of European Americans in Genetic Association Studies.


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